FRK and age-related macular degeneration: Recent additions to the growing list of potential AMD risk loci include 6q21–q22.3 that encompass two genes—the collagen, type X, alpha 1 gene and the fyn-related kinase gene—and 6p12 harboring the vascular endothelial growth factor A gene, which were identified through a recent large-scale meta-analysis of genome-wide association study for advanced AMD [17].