Furthermore, signals from EMID2_BL1_ht2 (unique to the minor alleles of rs6945102, rs4729697, rs221, and rs10435333, among the haplotypes with frequency > 0.05), EMID2_BL2_ht2 (unique to the minor alleles of rs4727494 and rs13233066), and EMID2_BL3_ht1 (unique to the minor alleles of rs1008064 and rs1543883) achieved significance (P = 0.0008-0.03, OR = 0.54-0.74 depending on the genetic model; Table 2 and Table S2) after analyzing the differences in the frequency distribution of EMID2 haplotypes between polyp-positive and polyp-negative asthma patients. Here, COL26A1 is linked to asthma.