In the present study we determined nucleosomes and other cell death parameter like cytokeratin-19 fragments (CYFRA 21-1), lactate dehydrogenase (LDH), the colorectal tumor related markers carcinoembryonic antigen (CEA) and cancer antigen 19-9 (CA 19-9) [27], the C-reactive protein (CRP) and classical liver parameters in the serum of patients undergoing SIRT in order to identify markers for predicting therapy response and indicating prognosis. The gene discussed is CEACAM5; the disease is colorectal neoplasm.