However, the tumour cells are also capable of secretion of these factors and may thereby recruit (e.g. by chemokine (C-C motif) ligand 17/22 (CCL17/22)) or lead to the differentiation of immunosuppressive cell types (e.g. by indolamine-2,3-dioxygenase 1 (IDO1) or Interleukin 10 (IL10)) [16]. The gene discussed is IL10; the disease is neoplasm.