The majority of cells derived from a given tissue expressed HMGCR at relatively similar levels regardless of differentiation status, such as pancreatic carcinoma cells (Capan 1, lane 4; MiaPaca, lane 5), breast (MCF-7, lane 10; SkBr3, lane 11), colon (Caco 2, lane 12; HCT116, lane 13), bladder (U9, lane 14; U14, lane 15), or squamous cell carcinoma (SCC-P9, lane 16; SCC-M7, lane 17). The gene discussed is HMGCR; the disease is exocrine pancreatic carcinoma.