As NF-κB and ALDH activities as well as CD44+ cell population have all been previously shown to regulate prostate cancer cell migration (Klarmann et al, 2009; Zhang et al, 2009b; van den Hoogen et al, 2010), the migratory effect of salinomycin was studied in prostate cancer cells. This evidence concerns the gene NFKB1 and prostate cancer.