Childhood-onset schizophrenia abnormalities identified by Addington and Rapoport [35] include 22q11, 45,X atypical/mosaic, 47,XXX, duplications of 16p11.2, MYT1L duplication on chromosome 2, and NRXN1 deletion on chromosome 2. This evidence concerns the gene MYT1L and schizophrenia.