TNF and cancer: The expression in cancer cells of the adipocyte enhancer binding protein 1 (AEBP1), a prominent gene of the signature known to bind in the promoter region of the adipocyte fatty-acid protein FABP4 may play an important role in that respect, as may also the presence of oxidative stress and TNF signaling suggested by the presence of TNFAIP6 and C1QTNF3 in the signature.