A subsequent analysis revealed a significant association of heterozygous (TG) and homozygous (GG) variant genotype of APE1 T1349G with the risk of gastric cancer (OR = 1.61, 95% CI = 1.12–2.32 for TG versus TT, and OR = 1.92, 95% CI = 1.23–2.99 for GG versus TT, respectively). This evidence concerns the gene APEX1 and gastric cancer.