MMP3 and atrial fibrillation: Further multivariate analysis adjusted for age, MMP-3, logMMP2, logMMP-9, ejection fraction, LAV and LAV/BSA showed that lower serum logTIMP-1 was the only independent factor associated with AF incidence (OR: 0.259, 95%CI: 0.104-0.645, p = 0.004), (Figure 3).