Our results support a similar role for LPC in prostate cancer cells since PLA2G7 silencing followed by reduced LPC levels resulted in changes in multiple adhesion molecules, such as decrease in the expression of cell-to-cell adhesion molecules NCAM1 and DSCAM, and increase in extracellular matrix binding ITGB1. The gene discussed is ITGB1; the disease is Familial prostate cancer.