CNR1 and hydrops fetalis: In order to evaluate the influence of dietary fat quality in relation to CB1 functioning in adipose tissue, we determined the expression levels of differentiation and proliferation markers, the rate of fatty acid synthesis and lipoprotein lipase (LPL) activity in epididymal fat pads of CB1+/+ and CB1-/- mice receiving a standard, low-fat chow diet, a high-fat (HF) or a HF diet in which part of the fat was replaced by fish oil (HF/FO diet).