Recently, DNA methylation and histone acetylation status of 5′ sequences of CD7 and ELA2, genes associated with CML clinical outcome, in leukaemic cell lines and primitive leukaemic cells from chronic phase CML patients have been reported to contribute to the variable expression of these two genes (6). The gene discussed is CD7; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.