To further study the possible mechanisms by which S100A4 modulated the growth, invasion and metastasis potential of SW620 cells, we purified total-RNA from the SW620-siS100A4 and SW620-siControl and used PCR array analysis to profile the expression of tumor metastasis-related genes in response to the knockdown of S100A4 expression in SW620 cells. The gene discussed is S100A4; the disease is neoplasm.