ZC3H12A and brain ischemia: The MCPIP1 mRNA level in the ipsilateral side of mouse brain was significantly induced after MCAO compared to the contralateral side; significant increase of MCPIP1 in transcript level was detected at 3 h and reached 9.85 ± 2.1 fold at 24 h after MCAO (P < 0.01; Figure 3), suggesting that MCPIP1 may play an important role after brain ischemia stress.