Lactation was associated with lower prevalence of diabetes and better glucose tolerance at 4-12 weeks postpartum; a lower total area under the glucose tolerance curve (AUC) (17.0 ± 4.2 vs. 17.9 ± 5.0 g.minute/dL), and lower fasting serum glucose (93 ± 13 vs. 98 ± 17 mg/dL) and 2-hour OGTT glucose levels (124 ± 41 vs. 134 ± 49 mg/dL) after controlling for body mass index (BMI), maternal age and insulin use during pregnancy [19]. The gene discussed is INS; the disease is diabetes mellitus.