Highly informative for the classification of neuroblastoma versus Wilms tumor was the ELAV-like protein 4 (ELAVL4) that is implicated in neuronal differentiation and has been associated with Parkinson's disease [33], the Microtubule-associated proteins (MAP) 1A/1B light chain 3A precursor that are microtubule-associated and mediate the interactions between cytoskeleton and microtubules [34], Amyloid beta A4 precursor protein-binding family B member 1 (APBB1) that plays a role in controlling neurogenesis of GnRH-1 neurons [35]. The gene discussed is GNRH1; the disease is Nephroblastoma.