ASDII was also reported to be overrepresented in patients with hypertrophic cardiomyopathy (HCM) or left-ventricular non-compaction cardiomyopathy (LVNC) caused by mutations in ACTC1 and MYH7 encoding the sarcomeric filaments alpha-actin and beta-myosin heavy chain, respectively [8], [9]. This evidence concerns the gene ACTC1 and left ventricular noncompaction.