Further studies are required to understand the mechanism of FSP27-mediated clustering and fusion of LDs in adipocytes as it applies to the efficiency and capacity of adipocytes to store TG in adipocytes, a phenomenon which is associated with the pathophysiology of diseases such as Type 2 diabetes and obesity [43], [44], [45], [46], [47]. Here, CIDEC is linked to obesity due to melanocortin 4 receptor deficiency.