In the bivariate analysis for the study of the factors associated with the outcome “TRAIL at time 1 - TRAIL at time 3” >20 pg/ml, it was observed that the women more at risk of a significant decrease in TRAIL at the partum were those: with higher age, nulliparous, with induction of labor, with operative vaginal delivery or urgent CS, who did not have analgesia during labor or with fetal distress (Table S1). Here, TNFSF10 is linked to Fetal distress.