A decrease in growth as a result of PPARγ knockdown is somewhat unexpected, given the accumulated data from numerous studies, mainly with PPARγ agonists, that would characterize PPARγ as a tumor suppressor that mediates many antitumorigenic activities such as induction of differentiation, promotion of cell cycle arrest, antiangiogenic effects, and induction of apoptosis [15]. Here, PPARG is linked to neoplasm.