LOXL1 and open-angle glaucoma: A recent genome-wide association study reported that one intronic single nucleotide polymorphism (SNP; rs2165241) and two exonic SNPs (rs1048661 [R141L], rs3825942 [G153D]) in the first exon of the lysyl oxidase-like 1 (LOXL1) gene on chromosome 15q24.1 are highly associated with EX in Icelandic and Swedish populations, and that none of these SNPs was associated with primary open-angle glaucoma in the two populations [4].