Mutations in three genes namely, myocilin (MYOC, earlier called as the TIGR- Trabecular meshwork Inducible Glucocorticoid Response gene), optineurin (OPTN), and W (tryptophan) D (aspartic acid) repeat 36 (WDR36) have been identified among POAG patients [19-24]. This evidence concerns the gene OPTN and open-angle glaucoma.