IL-10 levels were four-fold higher in scrub typhus than in murine typhus patients, suggesting a stronger anti-inflammatory tendency with suppression of other inflammatory cytokines such as TNF-α, IL-1β, and IL-6 (Table 2), especially in bacteraemic patients with scrub typhus, who had significantly higher IL-8 and IL-10 levels and significantly lower PAA levels on admission, in contrast to murine typhus patients, in whom no association between bacteraemia and cytokine levels was noted. This evidence concerns the gene IL10 and typhus.