Finally in our material interestingly in those carcinomas that were expressing ARs, stronger nuclear expression of the receptor was characterized by poorer cell differentiation and correlated with the acquisition of EMT features like E-cadherin loss and β-catenin translocation raising a question whether activated ARs can contribute together with other molecular pathways to the development of an Epithelial-Mesenchymal Transition in the course of laryngeal carcinoma metastasis. Here, CDH1 is linked to carcinoma.