In female, the prevalence of IgG and IgA antibodies towards Ct-MOMP antigen (major outer membrane protein) is mainly found in subjects with primary chlamydial infections, whereas the presence of antibodies against Ct-hsp60 and Ct-hsp10 is significantly higher in patients with recurrent or persistent infections. This evidence concerns the gene HSPD1 and chlamydia trachomatis infectious disease.