IL2RB and neoplasm: Following NK cell activation for 2 to 3 days after α-GalCer injection, bystander CD8+CD122+cells with NK cell-like antitumor activity without tumor-specificity are increased at 3 to 7 days after α-GalCer injection, while memory CD8+T cells, which are cytotoxic only against certain tumors, are induced within two weeks (Figure 1).