We found COX-2 expression to be restricted to PDAC samples, where several cell types, for example, tumor cells, CAFs, Langerhans Islet cells, and infiltrating immune cells in the tumor expressed this inflammatory mediator with significantly higher expression in the stroma than in tumor nests (P = 0.028) (Figures 3(e) and 3(f)). Here, PTGS2 is linked to neoplasm.