Furthermore, HCC cells themselves express various growth factors such as vascular endothelial growth factor (VEGF) [19], platelet-derived growth factor (PDGF) [20], epidermal growth factor (EGF) [21], fibroblast growth factor (FGF) [22], and insulin-like growth factor (IGF) [23], which induce cell proliferation in an autocrine fashion [24]. The gene discussed is VEGFA; the disease is hepatocellular carcinoma.