The prevalence of hypertension was higher at higher insulin and HOMA-IR values (P < 0.0001 in each); the odds ratio was 1.6 (95% CI: 1.4–2.0) and 1.6 (95% CI: 1.4–2.0) after controlling for age, sex, BMI, income level, parents' education level, and puberty, respectively (Table 3). The gene discussed is INS; the disease is Hypertension.