Epithelial cell adhesion molecule is expressed on normal epithelial cells and overexpressed in a variety of epithelial carcinomas, including pancreatic cancers where heterogeneous EpCAM expression is observed (Baeuerle and Gires, 2007; Trzpis et al, 2007; Fong et al, 2008; Munz et al, 2009). The gene discussed is EPCAM; the disease is familial pancreatic carcinoma.