TGFB1 and cancer: IFNG and MAPK14 are shown to be highly scored by TCGA gene tracker; TGFB1 is known to be upregulated in GBM [62]; PKC (Protein Kinase C) is well established in cancer signaling and therapy as it is involved in proliferation, migration, and malignant transformation [63], and its isozyme has been suggested for chemotherapeutic targets in GBM [64]; and ILB1 is down stream of NF-kB and is known to play an important role in cellular response to stress [65] and is constitutively activated in most tumor types.