Further adjustment for smoking, blood pressure, body mass index, serum albumin, myocardial infarction or stroke, the HR for patients with diabetes as primary renal disease was 1.8 (95% CI 1.3, 2.4) and 1.8 (95% CI 1.5, 2.3) for patients with diabetes as a co-morbid condition, as compared to non-diabetic patients. The gene discussed is ALB; the disease is stroke disorder.