CCND1 and non-small cell lung carcinoma: Particular gene polymorphisms may modify the susceptibility to NSCLC development, which includes the 308 G/A and 238 G/A polymorphisms in the promoter region of TNF-α, the cyclin D1 (CCND1) A870G gene polymorphism and the matrix metalloproteinase (MMP) 3 promoter polymorphism (12–14).