Vascular endothelial growth factor (VEGF) is a critical molecule involved in the pathogenesis of neovascular eye diseases such as neovascular age-related macular degeneration (AMD), proliferative diabetic retinopathy (PDR), diabetic macular edema (DME), retinal vein occlusion (RVO), and retinopathy of prematurity (ROP) [1]. The gene discussed is VEGFA; the disease is wet macular degeneration.