Thus, possible candidates for white coat colour (KIT on BTA6, KITLG on BTA5, PMEL on BTA5, TYR on BTA29) and other Waardenburg syndromes (WS) including PAX3 (WS1, WS3; on BTA2), EDNRB (WS4a; on BTA12), EDN3 (WS4b; on BTA13) and SOX10 (WS2e, WS4c; on BTA5) could be clearly excluded. The gene discussed is PMEL; the disease is Werner syndrome.