Furthermore, we found that FoxP3+ cells were also induced from CD4+CD25− T cells isolated from HVs in the presence of malignant B cells, and FoxP3+ cells could not be induced from CD4+CD25− T cells isolated from B-cell NHL specimens (patients 5 and 11 for BM, n = 2; patients 7 and 24 for involved LN, n = 2) in the presence of normal B cells (Figure 4C and 4D). The gene discussed is CD4; the disease is B-cell non-Hodgkin lymphoma.