Liver fibrosis was not correlated with STAT1-nuclear translocation in hepatocytes, but the activity of liver inflammation was correlated with STAT1-nuclear translocation in hepatocytes [mild activity (A1) vs. moderate activity (A2) and severe activity (A3): P = 0.0016 in zone 1; P = 0.00026 in zone 2; P = 0.0022 in zone 3; P = 0.00018 in all zones; data not shown]. The gene discussed is STAT1; the disease is Hepatic fibrosis.