In line with our in vitro findings, application of CAPs in an experimental model of murine acute myocarditis reduced cardiac apoptosis as shown by TUNEL staining (Figure 4C) and as indicated by a 1.6-fold (p<0.01) decrease in caspase 3/7 activity to levels not significantly different from controls (Figure 4D). Here, CASP3 is linked to myocarditis.