FoxM1 is expressed in glioma and pancreatic cancer cells and promotes angiogenesis by regulating VEGF expression [11, 12], FoxO1/3/4 act as tumor suppressors in prostate cancer and leukemia [13, 14], and recent evidence suggests that FoxC2 is a key factor in tumor development and disease progression. The gene discussed is FOXO1; the disease is neoplasm.