PTK2 and infection: Figure 2A shows an increase in FAK phosphorylation on tyrosine 397 in KSHV-infected cells, compared to mock-infected cells. Furthermore, Src is also phosphorylated more heavily on tyrosine 416 in KSHV-infected cells. These experiments were also performed in primary HMVECs, which upon infection undergo a small but reproducible increase in Fak and Src activation (Figure 2B).