IFIT2 and viral infectious disease: RAW264.7 cells infected at a low MOI (0.1 TCID50 per cell) with the M1 VF1 knockout virus exhibited a greater induction of antiviral genes such as ISG54, CXCL10 and IFN-Beta in response to viral infection than those infected with the WT virus (Figure 5A and Figure 5B).