At present, some tumor-associated genes have been identified near these loci, such as FHIT (3p), RASSF1A (3p), APC (5q), ANXI (9q), DEC1 (9q), RB1 (13q), BRCA2 (13q), ING1 (13q), and TP53 (17p). The gene discussed is TP53; the disease is neoplasm.