Samples from the goat with suspected BSE and samples from the experimentally BSE-infected goat and experimentally infected sheep generated equivalent PrPSc distribution patterns in PrP-a mice (Figure 2, panels A–F), which were clearly distinct from the PrPSc patterns generated by goat scrapie in the same mice (Figure 2, panels G and H). The gene discussed is PRNP; the disease is scrapie.