IL17A and neoplasm: When tumor cells were injected into nude mice, the growth rate of SMMC7721-IL-17 tumors was drastically increased relative to SMMC7721-mock controls [mean tumor volume (mock vs IL-17), 0.589 ± 0.259 vs 4.175 ± 3.050 cm3, p = 0.031; mean tumor weight (mock vs IL-17), 0.392 ± 0.124 vs 2.140 ± 0.963 g, p = 0.004; respectively; Figure 4A].