In the multivariable linear regression model (shown in Table 3), after adjustment for demographic (age, race, gender), anthropometric (BMI), socioeconomic (social support, medical insurance), lifestyle (smoking status), seasonal, comorbidity (diabetes and history of prior MI), treatment (in-hospital percutaneous coronary intervention [PCI] or coronary artery bypass graft [CABG]), laboratory (high sensitivity C-reactive protein [hs-CRP], estimated GFR) and medication (omega-3 supplement use) factors, 25(OH)D levels were not significantly associated with log NT-proBNP levels (P = 0.12). This evidence concerns the gene NPPB and diabetes mellitus.