Even though, mostly histone proteins 1-4 have been found inside apoptotic bodies as in the case of lymphoblasts [138], perhaps depending on the type of apoptotic induction and cell type, TNFR signaling proteins could remain encapsulated in these apoptotic bodies as in our case, and making it more intriguing is the fact that death receptor ligands, such as FasL and TRAIL have been found expressed on tumor microvesicles, albeit smaller than apoptotic bodies in size [139], in head and neck carcinoma from patients [140]. Here, TNFSF10 is linked to head and neck carcinoma.