On univariate overall survival analysis, performance status (P<0.05), T stage (P<0.001), tumour size (P<0.01), grade (P<0.001), necrosis (P<0.001), C-reactive protein (P<0.001) and mGPS (P<0.001) were significantly associated with overall survival (Table 3). This evidence concerns the gene CRP and neoplasm.