MMP14 and metastatic melanoma: Furthermore, four different metastatic melanoma cell lines tested (WM852, WM164, WM165 and WM239) as well as the Bowes, G361 and WM793 cells derived from non-metastatic primary melanoma all expressed MT1-MMP, whereas MT3-MMP was expressed in three cell lines originally isolated from metastatic melanomas (WM852, WM165 and WM239) and WM793 cell line isolated from advanced primary melanoma (Fig. 1C).