TLR3 and foot and mouth disease: Importantly, selection on TLR3 and TLR8 may have direct implications on aspects of differential susceptibility to major viral production diseases such as bluetongue (dsRNA; Reoviridae), foot and mouth disease (ssRNA; Picornaviridae), bovine viral diarrhea (ssRNA; Flaviviridae), calf coronavirus (ssRNA; neonatal diarrhea; Coronaviridae), and bovine parainfluenza 3 (ssRNA; Paramyxoviridae) (see [55], [56]).